Sex differences in the frailty phenotype and mortality in the I-Lan longitudinal aging study cohort.

ABSTRACT:

Background

Frailty is a common geriatric syndrome related to multiple adverse outcomes. Sex differences in its prevalence and impact on mortality remain incompletely understood.

Methods

This study was conducted with data from the I-Lan Longitudinal Aging Study, in which community-dwelling subjects aged > 50 years without coronary artery disease or diabetes were enrolled. Sex disparities in phenotypically defined frailty and sex-morality predictor interactions were evaluated. Sex- and frailty-stratified analyses of mortality were performed.

Results

The sample comprised 1371 subjects (51.4% women, median age 61 years). The median follow-up period was 6.3 (interquartile range, 5.8-7.0) years. The frailty prevalence did not differ between men (5.3%) and women (5.8%). Frai

SUBMITTER: Lu YW 

PROVIDER: S-EPMC10893742 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature