Subjective states induced by intracranial electrical stimulation matches the cytoarchitectonic organization of the human insula.

ABSTRACT: Functions of the human insula have been explored extensively with neuroimaging methods and intracranial electrical stimulation studies that have highlighted a functional segregation across its subregions. A recently developed cytoarchitectonic map of the human insula has also segregated this brain region into various areas. Our knowledge of the functional organization of this brain region at the level of these fine-parceled microstructural areas remains only partially understood. We address this gap of knowledge by applying a multimodal approach linking direct electrical stimulation and task-evoked intracranial EEG recordings with microstructural subdivisions of the human insular cortex. In 17 neurosurgical patients with 142 implanted electrodes, stimulation of 40 % of the sites induced a

SUBMITTER: Duong A 

PROVIDER: S-EPMC10893903 | biostudies-literature | 2023 Nov-Dec

REPOSITORIES: biostudies-literature