Distribution and prognostic value of high-sensitivity cardiac troponin T and I across glycemic status: a population-based study.

ABSTRACT:

Background

Whether distributions and prognostic values of high-sensitivity cardiac troponin (hs-cTn) T and I are different across normoglycemic, prediabetic, and diabetic populations is unknown.

Methods

10127 adult participants from the National Health and Nutrition Examination Survey 1999-2004 with determined glycemic status and measurement of at least one of hs-cTn assays were included, from whom healthy participants and presumably healthy diabetic and prediabetic participants were selected to investigate pure impacts of glycemic status on distributions of hs-cTn. The nonparametric method and bootstrapping were used to derive the 99th upper reference limits of hs-cTn and 95% CI. Participants with available follow-up and hs-cTn concentrations of all 4 assays were included i

SUBMITTER: Zhang J 

PROVIDER: S-EPMC10894468 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature