Biomarkers Assessing the Role of Cumulus Cells on IVF Outcomes: A Systematic Review.

ABSTRACT:

Purpose

Although significant improvements in assisted reproductive technology (ART) outcomes have been accomplished, a critical question remains: which embryo is most likely to result in a pregnancy? Embryo selection is currently based on morphological and genetic criteria; however, these criteria do not fully predict good-quality embryos and additional objective criteria are needed. The cumulus cells are critical for oocyte and embryo development. This systematic review assessed biomarkers in cumulus-oocyte complexes and their association with successful IVF outcomes.

Methods

A comprehensive search was conducted using PubMed, Embase, Scopus, and Web of Science from inception until November 2022. Only English-language publications were included. Inclusion criteria consisted

SUBMITTER: Massoud G 

PROVIDER: S-EPMC10894783 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature