Bacterial vaginosis in a subfertile population undergoing fertility treatments: a prospective cohort study.

ABSTRACT:

Purpose

This study investigates the role of bacterial vaginosis (BV) on pregnancy rates during various fertility treatments. BV is known to influence several obstetric outcomes, such as preterm delivery and endometritis. Only few studies investigated the effect of BV in subfertile women, and studies found a negative effect on fecundity especially in the in vitro fertilisation population.

Methods

Observational prospective study, 76 couples attending a fertility clinic in the Netherlands between July 2019 and June 2022, undergoing a total of 133 attempts of intra uterine insemination, in vitro fertilization or intra cytoplasmatic sperm injection. Vaginal samples taken at oocyte retrieval or insemination were analysed on qPCR BV and 16S rRNA gene microbiota analysis of V1-V2 re

SUBMITTER: van den Tweel MM 

PROVIDER: S-EPMC10894785 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature