The novel LESS (low-cost entrainment syringe system) O₂ blender for use in modified bubble CPAP circuits: a clinical study of safety.

ABSTRACT:

Background

Bubble continuous positive airway pressure (bCPAP) is used in resource-limited settings for children with respiratory distress. Low-cost modifications of bCPAP use 100% oxygen and may cause morbidity from oxygen toxicity. We sought to test a novel constructible low-cost entrainment syringe system (LESS) oxygen blender with low-cost modified bCPAP in a relevant clinical setting.

Methods

We conducted a clinical trial evaluating safety of the LESS O₂ blender among hospitalized children under five years old in rural Cambodia evaluating the rate of clinical failure within one hour of initiation of the LESS O₂ blender and monitoring for any other blender-related complications.

Findings

Thirty-two patients were included. The primary outcome (

SUBMITTER: Wu AG 

PROVIDER: S-EPMC10894966 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature