Damage evaluation of craniofacial localized scleroderma using magnetic resonance imaging.

ABSTRACT:

Background

Localized scleroderma (LoS) is an autoimmune disease in which craniofacial lesions can cause severe facial deformities with brain involvement. Objective evaluation of craniofacial LoS is challenging. Magnetic resonance imaging (MRI) may be used as a damage assessment tool. This study aimed to analyze the tissue involvement of craniofacial LoS based on MRI and evaluate MRI for craniofacial LoS assessment.

Methods

This cross-sectional study included patients with craniofacial LoS from September 2021 to August 2022 in Peking Union Medical College Hospital. Patients who were clinically assessed in a stable phase were enrolled; patients with previous surgical treatment or contraindications to MRI were excluded. Participants underwent clinical, MRI, and ultrasound asses

SUBMITTER: Ma X 

PROVIDER: S-EPMC10895148 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature