Outcomes of patients with traumatic brain injury after stress ulcer prophylaxis: a retrospective multicenter study.

ABSTRACT:

Background

Stress ulcers in patients with traumatic brain injury (TBI) and spinal cord injury (SCI) present significant morbidity and mortality risks. Despite the low reported stress ulcer rates, stress ulcer prophylaxis (SUP) is widely administered in neurocritical care. It was hypothesized that universal SUP administration may not be associated with reduced rates of complications across all neurocritical care patients.

Methods

This retrospective study encompassed neurocritical care patients aged ≥18 with moderate or severe TBI or SCI, admitted to the intensive care unit (ICU) between October 2020 and September 2021, across six level I trauma centers. Exclusions included patients with an ICU stay <2 days, prior SUP medication use, and pre-existing SUP diagnoses. The primary

SUBMITTER: McGraw C 

PROVIDER: S-EPMC10895230 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature