Cuproptosis-associated ncRNAs predict breast cancer subtypes.

ABSTRACT:

Background

Cuproptosis is a novel copper-dependent mode of cell death that has recently been discovered. The relationship between Cuproptosis-related ncRNAs and breast cancer subtypes, however, remains to be studied.

Methods

The aim of this study was to construct a breast cancer subtype prediction model associated with Cuproptosis. This model could be used to determine the subtype of breast cancer patients. To achieve this aim, 21 Cuproptosis-related genes were obtained from published articles and correlation analysis was performed with ncRNAs differentially expressed in breast cancer. Random forest algorithms were subsequently utilized to select important ncRNAs and build breast cancer subtype prediction models.

Results

A total of 94 ncRNAs significantly associated w

SUBMITTER: Xia Q 

PROVIDER: S-EPMC10896520 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature