The effect of teriparatide on patients with atypical femur fractures: a systematic review and meta-analysis.

ABSTRACT:

Introduction

Bisphosphonates (BPs) are one of the most often used drugs to lower fracture risk in osteoporosis patients; nonetheless, BPs have been linked to atypical femoral fracture (AFF). Teriparatide (TPTD) is a parathyroid hormone analogue and anabolic drug that may accelerate fracture repair. TPTD has been considered as a possible treatment for AFF, particularly those caused by BP use. We evaluate the effect of TPTD on AFF in this systematic review and meta-analysis.

Materials and methods

A thorough search of: Web of Science, Scopus, PubMed, and Cochrane was conducted on August 2, 2023. Trials evaluating the effect of TPTD on the incidence of: complete bone healing, non-union, early and delayed bone union, progression of incomplete AFF to complete AFF, and time to bone

SUBMITTER: Salamah HM 

PROVIDER: S-EPMC10896930 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature