Benefits and Harms of Mammography Screening in 75 + Women to Inform Shared Decision-making: a Simulation Modeling Study.

ABSTRACT:

Background

Guidelines recommend shared decision-making (SDM) around mammography screening for women ≥ 75 years old.

Objective

To use microsimulation modeling to estimate the lifetime benefits and harms of screening women aged 75, 80, and 85 years based on their individual risk factors (family history, breast density, prior biopsy) and comorbidity level to support SDM in clinical practice.

Design, setting, and participants

We adapted two established Cancer Intervention and Surveillance Modeling Network (CISNET) models to evaluate the remaining lifetime benefits and harms of screening U.S. women born in 1940, at decision ages 75, 80, and 85 years considering their individual risk factors and comorbidity levels. Results were summarized for average- and higher-risk women

SUBMITTER: Jayasekera J 

PROVIDER: S-EPMC10897118 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature