Therapeutic efficacy of probiotics for symptoms of attention-deficit hyperactivity disorder in children and adolescents: meta-analysis.

ABSTRACT:

Background

The efficacy of probiotics as a therapeutic alternative for attention-deficit hyperactivity disorder (ADHD) remain unclear.

Aims

To investigate the effectiveness of probiotics for symptoms of ADHD and identify possible factors affecting their efficacy.

Method

Randomised placebo-controlled trials were identified through searching major databases from inception to April 2023, using the main keywords 'probiotics' and 'ADHD' without limitation on languages or geographic locations. The outcome of interest included improvement in total symptoms of ADHD, symptoms of inattention and hyperactivity/impulsivity, and drop-out rate. Continuous and categorical data were expressed as effect sizes based on standardised mean differences (SMDs) and odds ratios, respectively,

SUBMITTER: Liang SC 

PROVIDER: S-EPMC10897698 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature