Membranes are functionalized by a proteolipid code.

ABSTRACT: Membranes are protein and lipid structures that surround cells and other biological compartments. We present a conceptual model wherein all membranes are organized into structural and functional zones. The assembly of zones such as receptor clusters, protein-coated pits, lamellipodia, cell junctions, and membrane fusion sites is explained to occur through a protein-lipid code. This challenges the theory that lipids sort proteins after forming stable membrane subregions independently of proteins.

SUBMITTER: Kervin TA 

PROVIDER: S-EPMC10898092 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature