Membranes are functionalized by a proteolipid code.
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ABSTRACT:
SUBMITTER: Kervin TA
PROVIDER: S-EPMC10898092 | biostudies-literature | 2024 Feb
REPOSITORIES: biostudies-literature
Publications
Membranes are functionalized by a proteolipid code.
Kervin Troy A TA Overduin Michael M
BMC biology 20240227 1
Membranes are protein and lipid structures that surround cells and other biological compartments. We present a conceptual model wherein all membranes are organized into structural and functional zones. The assembly of zones such as receptor clusters, protein-coated pits, lamellipodia, cell junctions, and membrane fusion sites is explained to occur through a protein-lipid code. This challenges the theory that lipids sort proteins after forming stable membrane subregions independently of proteins. ...[more]
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