The relationship between inflammatory cytokines and in-hospital complications of acute pancreatitis.

ABSTRACT:

Objective

Acute necrotic collection (ANC), acute peripancreatic fluid collection (APFC), pleural effusion, and ascites are common early complications of acute pancreatitis. This study aimed to investigate the relationship between 12 serum cytokines and the early complications and severity of acute pancreatitis (AP).

Methods

We retrospectively analyzed the clinical data of 307 patients with AP, and divided them into severe group and mild-to-moderate group according to the revised Atlanta classification. Propensity score matching was used to control for confounding factors. Binary logistic regression analysis was used to explore the relationship between cytokine levels and early complications of AP.

Results

Serum levels of interleukin (IL)-1β, IL-5, IL-6, IL-8, IL-10, I

SUBMITTER: Yao J 

PROVIDER: S-EPMC10898203 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature