Biopolymer-protected graphene-Fe₃O₄ nanocomposite based wearable microneedle sensor: toward real-time continuous monitoring of dopamine.

ABSTRACT: Neurological disorders can occur in the human body as a result of nano-level variations in the neurotransmitter levels. Patients affected by neuropsychiatric disorders, that are chronic require continuous monitoring of these neurotransmitter levels for effective disease management. The current work focus on developing a highly sensitive and personalized sensor for continuous monitoring of dopamine. Here we propose a wearable microneedle-based electrochemical sensor, to continuously monitor dopamine in interstitial fluid (ISF). A chitosan-protected hybrid nanomaterial Fe₃O₄-GO composite has been used as a chemical recognition element protected by Nafion antifouling coating layer. The morphological and physiochemical characterizations of the nanocomposite were carried o

SUBMITTER: M R K 

PROVIDER: S-EPMC10898425 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature