Morphine exposure modulates dimensional bias and set formation in anthropoids.

ABSTRACT: Humans demonstrate significant behavioural advantages with particular perceptual dimensions (such as colour or shape) and when the relevant dimension is repeated in consecutive trials. These dimension-related behavioural modulations are significantly altered in neuropsychological and addiction disorders; however, their underlying mechanisms remain unclear. Here, we studied whether these behavioural modulations exist in other trichromatic primate species and whether repeated exposure to opioids influences them. In a target detection task where the target-defining dimension (colour or shape) changed trial by trial, humans exhibited shorter response time (RT) and smaller event-related electrodermal activity with colour dimension; however, macaque monkeys had shorter RT with shape dimension. A

SUBMITTER: Ghasemian S 

PROVIDER: S-EPMC10898839 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature