In-vivo integration of soft neural probes through high-resolution printing of liquid electronics on the cranium.

ABSTRACT: Current soft neural probes are still operated by bulky, rigid electronics mounted to a body, which deteriorate the integrity of the device to biological systems and restrict the free behavior of a subject. We report a soft, conformable neural interface system that can monitor the single-unit activities of neurons with long-term stability. The system implements soft neural probes in the brain, and their subsidiary electronics which are directly printed on the cranial surface. The high-resolution printing of liquid metals forms soft neural probes with a cellular-scale diameter and adaptable lengths. Also, the printing of liquid metal-based circuits and interconnections along the curvature of the cranium enables the conformal integration of electronics to the body, and the cranial circuit del

SUBMITTER: Park YG 

PROVIDER: S-EPMC10899244 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature