Premature Infant Gut Microbiome relationships with childhood behavioral scales: preliminary insights.

ABSTRACT:

Introduction

Very Low Birth Weight (VLBW) infants, born weighing less than 1,500 grams, are at risk for both gut dysbiosis and later neuropsychological developmental deficits. Behavioral effects, while related to neurodevelopment, are often more subtle and difficult to measure. The extent of later neurobehavioral consequences associated with such microbial dysbiosis has yet to be determined. We explored associations between the infants' gut microbiome and early childhood behavior at 4 years of age and identified the bacterial taxa through a multivariate analysis by linear models.

Methods

Parents completed the Child Behavior Checklist (CBCL) focused on different DSM diagnostic categories: affective, anxiety, pervasive developmental, attention deficit/hyperactivity, and opposi

SUBMITTER: Ozorio Dutra SV 

PROVIDER: S-EPMC10899318 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature