Higher perfusion pressure and pump flow during cardiopulmonary bypass are beneficial for kidney function-a single-centre prospective study.

ABSTRACT: Background: Kidneys play an essential role in the circulatory system, regulating blood pressure and intravascular volume. They are also set on maintaining an adequate filtration pressure in the glomerulus. During the CPB, a decrease in systemic blood pressure and hemoglobin concentration may lead to renal ischemia and subsequent acute kidney injury. Methods: One hundred nine adult patients were prospectively enrolled in this study. The intervention in this study was increasing the flow of the CPB pump to reach the target MAP of > 90 mmHg during the procedure. The control group had a standard pump flow of 2.4 L/min/m². Results: Standard pump flow of 2.4 L/min/m² resulted in mean MAP < 90 mmHg during the CPB in most patients in the control group. Ma

SUBMITTER: Udzik J 

PROVIDER: S-EPMC10899324 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature