Living Donor Liver Transplantation for Adults With High Model for End-stage Liver Disease Score: The US Experience.

ABSTRACT:

Background

Outcomes after living-donor liver transplantation (LDLT) at high Model for End-stage Liver Disease (MELD) scores are not well characterized in the United States.

Methods

This was a retrospective cohort study using Organ Procurement and Transplantation Network data in adults listed for their first liver transplant alone between 2002 and 2021. Cox proportional hazards models evaluated the association of MELD score (<20, 20-24, 25-29, and ≥30) and patient/graft survival after LDLT and the association of donor type (living versus deceased) on outcomes stratified by MELD.

Results

There were 4495 LDLTs included with 5.9% at MELD 25-29 and 1.9% at MELD ≥30. LDLTs at MELD 25-29 and ≥30 LDLT have substantially increased since 2010 and 2015, respectively. Patient sur

SUBMITTER: Rosenthal BE 

PROVIDER: S-EPMC10899524 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature