A retrospective study on adverse events of intravenous administration of sulfur hexafluoride microbubbles in abdominal and superficial applications in 83,778 patients.

ABSTRACT:

Objectives

To investigate the rate of adverse events (AEs) caused by intravenous administration of sulfur hexafluoride microbubbles in abdominal and superficial applications retrospectively and to explore practical measures for prevention and treatment of them.

Materials and methods

This study enrolled 83,778 contrast-enhanced ultrasound (CEUS) examinations using sulfur hexafluoride microbubbles intravenously performed during 11 years. Age, gender, and target organs of all CEUS patients were recorded. For cases of AEs, their medical history and laboratory results were also collected. The process of AEs was assessed and categorized. Besides, the management of AEs were recorded.

Results

Twenty patients had sulfur hexafluoride microbubbles-related AEs. The AE rate was 0.

SUBMITTER: Li D 

PROVIDER: S-EPMC10899544 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature