Association between obstructive sleep apnea and low bone mass in adults: a systematic review and meta-analysis.

ABSTRACT:

Introduction

This study aimed to synthesize existing evidence on the potential association between obstructive sleep apnea (OSA) and low bone mass in adults.

Methods

Electronic searches of four main databases were performed. The inclusion criteria consisted of observational studies investigating the relationship between OSA and bone mass, osteoporosis, fractures, or bone metabolism markers in adult population. Bone mineral density (BMD) and T score of lumbar and femur neck, incidence of osteoporosis and fractures, bone metabolism marker levels were extracted as primary outcomes.

Results

Among the 693 relevant publications, 10 studies consisting of 158,427 participants met with the inclusion and exclusion criteria. Meta-analysis showed a significant lower BMD of lumbar

SUBMITTER: Wang XY 

PROVIDER: S-EPMC10899924 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature