Long-term ozone exposure and mortality in patients with chronic kidney disease: a large cohort study.

ABSTRACT:

Background

Epidemiologic studies on the effects of long-term exposure to ozone (O₃) have shown inconclusive results. It is unclear whether to O₃ has an effect on chronic kidney disease (CKD). We investigated the effects of O₃ on mortality and renal outcome in CKD.

Methods

We included 61,073 participants and applied Cox proportional hazards models to examine the effects of ozone on the risk of end-stage renal disease (ESRD) and mortality in a two-pollutants model adjusted for socioeconomic status. We calculated the concentration of ozone exposure one year before enrollment and used inverse distance weighting (IDW) for interpolation, where the exposure was evenly distributed.

Results

In the single pollutant model, O₃ was signi

SUBMITTER: Kim E 

PROVIDER: S-EPMC10900590 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature