Hepatitis B vaccine effectiveness among vaccinated children in Africa: a systematic review and meta-analysis.

ABSTRACT:

Background

Globally, 257 million people have chronic hepatitis. Even though a safe and effective prophylactic vaccine against HBV infection has been available, it causes significant morbidity and mortality. HBV vaccines were designed to improve or modulate the host immune responses. The effectiveness of the vaccine is determined by measuring serum hepatitis B surface antibody (Anti-HBs) level. Therefore, this systematic review aimed to evaluate the effectiveness of hepatitis B vaccine among vaccinated children.

Methods

Preferred reporting items for systematic review and meta-analysis (PRISMA) guidelines was applied for systematically searching of different databases. Only cross-section studies measuring the level of anti-HBs of vaccinated children were included. The seroprot

SUBMITTER: Geta M 

PROVIDER: S-EPMC10900737 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature