Real-world effectiveness of erenumab in Japanese patients with migraine.

ABSTRACT:

Background

Real-world evidence of erenumab effectiveness in migraine patients in Asia with various comorbidities and multiple previous medication failures is still limited.

Methods

A 6-month single-center cohort study of 45 patients with episodic or chronic migraine (CM) treated with erenumab was conducted. In the cohort, 60.0% were switching from other calcitonin gene-related peptide monoclonal antibodies (CGRP mAbs), and 66.7% had ≥4 prophylaxis failures. The change in monthly migraine days (MMDs) from baseline and percentages of responders after treatment were calculated. Weekly migraine days (WMDs) were obtained at baseline and at months 1, 2 and 3 and were compared between weeks 2 and 4.

Results

In total, 36%, 47%, and 63% of patients had a ≥30% response at 1, 3,

SUBMITTER: Suzuki K 

PROVIDER: S-EPMC10900787 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature