Genomic epidemiology and antifungal-resistant characterization of Candida auris, Colombia, 2016-2021.

ABSTRACT: Since 2016, in Colombia, ongoing transmission of Candida auris has been reported in multiple cities. Here, we provide an updated description of C. auris genomic epidemiology and the dynamics of antifungal resistance in Colombia. We sequenced 99 isolates from C. auris cases with collection dates ranging from June 2016 to January 2021; the resulting sequences coupled with 103 previously generated sequences from C. auris cases were described in a phylogenetic analysis. All C. auris cases were clade IV. Of the 182 isolates with antifungal susceptibility data, 67 (37%) were resistant to fluconazole, and 39 (21%) were resistant to amphotericin B. Isolates predominately clustered by country except for 16 isolates from Bogotá, Colombia, which grouped with isolate

SUBMITTER: Misas E 

PROVIDER: S-EPMC10900874 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature