Female Sex and Mortality in Patients with Staphylococcus aureus Bacteremia: A Systematic Review and Meta-analysis.

ABSTRACT:

Importance

Staphylococcus aureus is the leading cause of death due to bacterial bloodstream infection. Female sex has been identified as a risk factor for mortality in S aureus bacteremia (SAB) in some studies, but not in others.

Objective

To determine whether female sex is associated with increased mortality risk in SAB.

Data sources

MEDLINE, Embase, and Web of Science were searched from inception to April 26, 2023.

Study selection

Included studies met the following criteria: (1) randomized or observational studies evaluating adults with SAB, (2) included 200 or more patients, (3) reported mortality at or before 90 days following SAB, and (4) reported mortality stratified by sex. Studies on specific subpopulations (eg, dialysis, intensive care units, cancer pa

SUBMITTER: Westgeest AC 

PROVIDER: S-EPMC10900971 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature