Efficacy of a combination of esafoxolaner, eprinomectin and praziquantel (NexGard^® Combo) against Thelazia callipaeda in naturally infected cats.

ABSTRACT: This clinical study assessed the efficacy of a topical combination of esafoxolaner, eprinomectin and praziquantel (NexGard^® Combo) in treating cats naturally infected with the eyeworm Thelazia callipaeda (Nematoda, Thelaziidae). On Study Day (SD) 0, sixteen client-owned cats with eyeworm infection were allocated to an untreated control group (G1, 8 cats) or to a NexGard^® Combo treated group (G2, 8 cats) and subjected to ocular examination. Cats in G2 received the treatment as per label recommendations. On SD 7 and 14 (±1), cats were examined for the presence of eyeworms and clinical signs. On SD 14, eyeworms were collected and counted. On SD 7 and 14, all cats in G1 were still infected with eyeworms, while G2 cats were free from eyeworms on SD 7 and 14, demonstrating

SUBMITTER: Di Cesare A 

PROVIDER: S-EPMC10901074 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature