Photoacoustic/ultrasound dual-modality imaging for marker clip localization in neoadjuvant chemotherapy of breast cancer.

ABSTRACT:

Significance

To ensure precise tumor localization and subsequent pathological examination, a metal marker clip (MC) is placed within the tumor or lymph node prior to neoadjuvant chemotherapy for breast cancer. However, as tumors decrease in size following treatment, detecting the MC using ultrasound imaging becomes challenging in some patients. Consequently, a mammogram is often required to pinpoint the MC, resulting in additional radiation exposure, time expenditure, and increased costs. Dual-modality imaging, combining photoacoustic (PA) and ultrasound (US), offers a promising solution to this issue.

Aim

Our objective is to localize the MC without radiation exposure using PA/US dual-modality imaging.

Approach

A PA/US dual-modality imaging system was developed. Utili

SUBMITTER: Deng H 

PROVIDER: S-EPMC10901241 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature