Prefrontal theta-gamma transcranial alternating current stimulation improves non-declarative visuomotor learning in older adults.

ABSTRACT: The rise in the global population of older adults underscores the significance to investigate age-related cognitive disorders and develop early treatment modalities. Previous research suggests that non-invasive transcranial Alternating Current Stimulation (tACS) can moderately improve cognitive decline in older adults. However, non-declarative cognition has received relatively less attention. This study investigates whether repeated (16-day) bilateral theta-gamma cross-frequency tACS targeting the Dorsolateral Prefrontal Cortex (DLPFC) enhances non-declarative memory. Computerized cognitive training was applied alongside stimulation to control for the state-of-the-brain. The Alternating Serial Reaction Time (ASRT) task was employed to assess non-declarative functions such as visuomotor ski

SUBMITTER: Diedrich L 

PROVIDER: S-EPMC10901881 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature