Comparison of computational fluid dynamics with transcranial Doppler ultrasound in response to physiological stimuli.

ABSTRACT: Cerebrovascular haemodynamics are sensitive to multiple physiological stimuli that require synergistic response to maintain adequate perfusion. Understanding haemodynamic changes within cerebral arteries is important to inform how the brain regulates perfusion; however, methods for direct measurement of cerebral haemodynamics in these environments are challenging. The aim of this study was to assess velocity waveform metrics obtained using transcranial Doppler (TCD) with flow-conserving subject-specific three-dimensional (3D) simulations using computational fluid dynamics (CFD). Twelve healthy participants underwent head and neck imaging with 3 T magnetic resonance angiography. Velocity waveforms in the middle cerebral artery were measured with TCD ultrasound, while diameter and velocity w

SUBMITTER: Caddy HT 

PROVIDER: S-EPMC10902019 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature