Bioenergetics of simultaneous oxygen and nitrate respiration and nitric oxide production in a Pseudomonas aeruginosa agar colony biofilm.

ABSTRACT: Pseudomonas aeruginosa is a biofilm forming pathogen commonly associated with infection of the cystic fibrosis (CF) lung, chronic wounds and indwelling medical devices. P. aeruginosa is a facultative aerobe that can use nitrate (NO₃^-) found in healthy and infected tissues and body fluids to generate energy through denitrification. Further, P. aeruginosa the expression of denitrification genes has been found in specimens from people with CF. The main aim of this study was to determine the relative energy contribution of oxygen (O₂) respiration and denitrification in single Pseudomonas aeruginosa PAO1 biofilm colonies under different O₂ concentrations to estimate the possible relative importance of these metabolic proces

SUBMITTER: Stoodley P 

PROVIDER: S-EPMC10902143 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature