Facile synthesis of nanoparticles-stacked Co₃O₄ nanoflakes with catalase-like activity for accelerating wound healing.

ABSTRACT: Delayed wound healing caused by excessive reactive oxygen species (ROS) remains a considerable challenge. In recent years, metal oxide nanozymes have gained significant attention in biomedical research. However, a comprehensive investigation of Co₃O₄-based nanozymes for enhancing wound healing and tissue regeneration is lacking. This study focuses on developing a facile synthesis method to produce high-stability and cost-effective Co₃O₄ nanoflakes (NFs) with promising catalase (CAT)-like activity to regulate the oxidative microenvironment and accelerate wound healing. The closely arranged Co₃O₄ nanoparticles (NPs) within the NFs structure result in a significantly larger surface area, thereby amplifying the enzymatic activit

SUBMITTER: Huang Y 

PROVIDER: S-EPMC10902680 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature