Patient-Reported Outcomes and Mortality in Cutaneous Chronic Graft-vs-Host Disease.

ABSTRACT:

Importance

Chronic graft-vs-host disease (GVHD) is associated with impaired quality of life and symptom burden. The independent association of skin involvement with patient-reported outcomes (PROs) and their utility as a clinical prognostic marker remain unknown. Identification of patients with cutaneous chronic GVHD and impaired PROs could assist in initial risk stratification and treatment selection.

Objective

To compare the association of sclerotic and epidermal-type chronic GVHD with longitudinal PROs and to evaluate whether PROs can identify patients with cutaneous chronic GVHD at high risk for death.

Design, setting, and participants

This multicenter prospective cohort study involved patients from the Chronic GVHD Consortium of 9 US medical centers, enrolled bet

SUBMITTER: Baumrin E 

PROVIDER: S-EPMC10902778 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature