Neurons in the monkey frontopolar cortex encode learning stage and goal during a fast learning task.

ABSTRACT: The frontopolar cortex (FPC) is, to date, one of the least understood regions of the prefrontal cortex. The current understanding of its function suggests that it plays a role in the control of exploratory behaviors by coordinating the activities of other prefrontal cortex areas involved in decision-making and exploiting actions based on their outcomes. Based on this hypothesis, FPC would drive fast-learning processes through a valuation of the different alternatives. In our study, we used a modified version of a well-known paradigm, the object-in-place (OIP) task, to test this hypothesis in electrophysiology. This paradigm is designed to maximize learning, enabling monkeys to learn in one trial, which is an ability specifically impaired after a lesion of the FPC. We showed that FPC neuron

SUBMITTER: Nougaret S 

PROVIDER: S-EPMC10903959 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature