Association of PM _2.5 Reduction with Improved Kidney Function: A Nationwide Quasiexperiment among Chinese Adults.

ABSTRACT: Background. Increasing evidence from human studies has revealed the adverse impact of ambient fine particles (PM _2.5) on health outcomes related to metabolic disorders and distant organs. Whether exposure to ambient PM _2.5 leads to kidney impairment remains unclear. The rapid air quality improvement driven by the clean air actions in China since 2013 provides an opportunity for a quasiexperiment to investigate the beneficial effect of PM _2.5 reduction on kidney function.Methods. Based on two repeated nationwide surveys of the same population of 5115 adults in 2011 and 2015, we conducted a difference-in-difference study. Variations in long-term exposure to ambient PM _2.5 were associated with changes in kidney function biomarkers, inc

SUBMITTER: Han Y 

PROVIDER: S-EPMC10904065 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature