Angiography‑based quantitative flow ratio for functional assessment of intracranial atherosclerotic disease.

ABSTRACT:

Background

Intracranial atherosclerotic stenosis (ICAS), an important cause of stroke, is associated with a considerable stroke recurrence rate despite optimal medical treatment. Further assessment of the functional significance of ICAS is urgently needed to enable individualised treatment and, thus, improve patient outcomes.

Aims

We aimed to evaluate the haemodynamic significance of ICAS using the quantitative flow ratio (QFR) technique and to develop a risk stratification model for ICAS patients.

Methods

Patients with moderate to severe stenosis of the middle cerebral artery, as shown on angiography, were retrospectively enrolled. For haemodynamic assessment, the Murray law-based QFR (μQFR) was performed on eligible patients. Multivariate logistic regression models

SUBMITTER: Huang K 

PROVIDER: S-EPMC10905197 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature