Retinoblastoma treatment in a Brazilian population. Presentation and long-term results.

ABSTRACT:

Introduction

Retinoblastoma is a malignant tumor with a high cure potential when proper therapy is used. The purpose of this paper is to report the clinical features and outcomes of patients with retinoblastoma who were treated with a combination of local and systemic chemotherapy-based protocols.

Method

We retrospectively studied patients treated with systemic chemotherapy plus local treatment between 2003 and 2015 with a follow-up ≥2 years. We correlated clinical and pathological characteristics with decimal visual acuity (VA) and death.

Results

Among 119 patients, 60% had unilateral disease (UNI), and 52% were male. The median presentation age was 19.5 months, 10% had a positive family history, and the most frequent sign was leukocoria (68.8%). Advanced disease was

SUBMITTER: Bonanomi MTBC 

PROVIDER: S-EPMC10905530 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature