Multi-Institutional Experience of Stereotactic Ablative Radiation Therapy for Stage I Small Cell Lung Cancer.

ABSTRACT:

Purpose

For inoperable stage I (T1-T2N0) small cell lung cancer (SCLC), national guidelines recommend chemotherapy with or without conventionally fractionated radiation therapy. The present multi-institutional cohort study investigated the role of stereotactic ablative radiation therapy (SABR) for this population.

Methods and materials

The clinical and treatment characteristics, toxicities, outcomes, and patterns of failure were assessed in patients with histologically confirmed stage T1-T2N0M0 SCLC. Kaplan-Meier analysis was used to evaluate the survival outcomes. Univariate and multivariate analyses identified predictors of outcomes.

Results

From 24 institutions, 76 lesions were treated in 74 patients (median follow-up 18 months). The median age and tumor size was 7

SUBMITTER: Verma V 

PROVIDER: S-EPMC10905608 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature