More severe initial manifestations and worse short-term functional outcome of intracerebral hemorrhage in the plateau than in the plain.

ABSTRACT: Intracerebral hemorrhage (ICH) is one of the most devastating forms of stroke. However, studies on ICH at high altitude are insufficient. We aimed to compare the initial manifestations, imaging features and short-term functional outcomes of ICH at different altitudes, and further explore the effect of altitude on the severity and prognosis of ICH. We retrospectively recruited ICH patients from January 2018 to July 2021 from two centers at different altitudes in China. Information regarding to clinical manifestations, neuroimages, and functional outcomes at discharge were collected and analyzed. Association between altitude and initial severity, neuroimages, and short-term prognosis of ICH were also investigated. A total of 724 patients with 400 lowlanders and 324 highlanders were enrolled.

SUBMITTER: Wang X 

PROVIDER: S-EPMC10905638 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature