The growth factor multimodality on treating human dental mesenchymal stem cells: a systematic review.

ABSTRACT:

Background

Ensuring the quantity, quality, and efficacy of human dental mesenchymal stem cells (MSCs) has become an urgent problem as their applications increase. Growth factors (GFs) have low toxicity, good biocompatibility, and regulate stem cell survival and differentiation. They bind to specific receptors on target cells, initiating signal transduction and triggering biological functions. So far, relatively few studies have been conducted to summarize the effect of different GFs on the application of dental MSCs. We have reviewed the literature from the past decade to examine the effectiveness and mechanism of applying one or multiple GFs to human dental MSCs. Our review is based on the premise that a single dental MSC cannot fulfill all applications and that different dental M

SUBMITTER: He H 

PROVIDER: S-EPMC10905837 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature