Efficient organized colorectal cancer screening in Shenzhen: a microsimulation modelling study.

ABSTRACT:

Background

Colorectal cancer (CRC) is a global health issue with noticeably high incidence and mortality. Microsimulation models offer a time-efficient method to dynamically analyze multiple screening strategies. The study aimed to identify the efficient organized CRC screening strategies for Shenzhen City.

Methods

A microsimulation model named CMOST was employed to simulate CRC screening among 1 million people without migration in Shenzhen, with two CRC developing pathways and real-world participation rates. Initial screening included the National Colorectal Polyp Care score (NCPCS), fecal immunochemical test (FIT), and risk-stratification model (RS model), followed by diagnostic colonoscopy for positive results. Several start-ages (40, 45, 50 years), stop-ages (70, 75, 80 

SUBMITTER: Zhu M 

PROVIDER: S-EPMC10905924 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature