Deciphering the omicron variant: integrated omics analysis reveals critical biomarkers and pathophysiological pathways.

ABSTRACT:

Background

The rapid emergence and global dissemination of the Omicron variant of SARS-CoV-2 have posed formidable challenges in public health. This scenario underscores the urgent need for an enhanced understanding of Omicron's pathophysiological mechanisms to guide clinical management and shape public health strategies. Our study is aimed at deciphering the intricate molecular mechanisms underlying Omicron infections, particularly focusing on the identification of specific biomarkers.

Methods

This investigation employed a robust and systematic approach, initially encompassing 15 Omicron-infected patients and an equal number of healthy controls, followed by a validation cohort of 20 individuals per group. The study's methodological framework included a comprehensive multi-o

SUBMITTER: Yang Q 

PROVIDER: S-EPMC10905948 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature