Chloroform associated with bone mineral density and bone mineral content in adults: A population-based cross-sectional research.

ABSTRACT:

Background

Bone mineral density is an important indicator of osteoporosis, and its variation with volatile organic compounds exposure has rarely been studied. However, the relationship between chloroform (an essential volatile organic compounds component) and bone mineral density remains unclear. Consequently, we aimed to explore the relationship between chloroform alone and bone mineral density or bone mineral content.

Methods

Herein, 2,553 individuals aged 18 and above from the National Health and Nutrition Examination Surveys (NHANES) in 2009-2010, 2013-2014, and 2017-2020, were included. We employed two independent t-tests and multi-linear regression models to statistically assess the relationship between chloroform exposure and BMD/BMC in the spine and femoral area.

SUBMITTER: Li L 

PROVIDER: S-EPMC10906833 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature