Associations between birth weight and adult apolipoproteins: The LifeGene cohort.

ABSTRACT:

Background

Early life factors may predict cardiovascular disease (CVD), but the pathways are still unclear. There is emerging evidence of an association of early life factors with apolipoproteins, which are linked to CVD. The study objective was to assess the associations between birth variables and adult apolipoproteins (apoA1 and apoB, and their ratio) in a population-based cohort.

Methods

The LifeGene Study is a prospective cohort comprising index participants randomly sampled from the general population. Blood samples were collected between 2009 and 2016. In this sub-study, we used birth variables, obtained from a national registry for all participants born 1973 or later, including birth weight and gestational age, while adult CVD risk factors included age, sex, body mas

SUBMITTER: Sharma S 

PROVIDER: S-EPMC10906835 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature