Ontology highlight
ABSTRACT:
SUBMITTER: Sprague JL
PROVIDER: S-EPMC10907035 | biostudies-literature | 2024 Mar
REPOSITORIES: biostudies-literature
Sprague Jakob L JL Schille Tim B TB Allert Stefanie S Trümper Verena V Lier Adrian A Großmann Peter P Priest Emily L EL Tsavou Antzela A Panagiotou Gianni G Naglik Julian R JR Wilson Duncan D Schäuble Sascha S Kasper Lydia L Hube Bernhard B
PLoS pathogens 20240301 3
The opportunistic fungal pathogen Candida albicans thrives on human mucosal surfaces as a harmless commensal, but frequently causes infections under certain predisposing conditions. Translocation across the intestinal barrier into the bloodstream by intestine-colonizing C. albicans cells serves as the main source of disseminated candidiasis. However, the host and microbial mechanisms behind this process remain unclear. In this study we identified fungal and host factors specifically involved in ...[more]