Auditory Cortical Plasticity in Patients with Single-Sided Deafness Before and After Cochlear Implantation.

ABSTRACT:

Purpose

This study investigated neuroplastic changes induced by postlingual single-sided deafness (SSD) and the effects of a cochlear implantation for the deaf ear. Neural processing of acoustic signals from the normal hearing ear to the brain was studied before and after implantation using a positron emission tomography (PET)/CT scanner.

Methods

Eight patients with postlingual SSD received a cochlear implant (CI) in a prospective clinical trial. Dynamic imaging was performed in a PET/CT scanner using radioactively labeled water ([15O]H2O) to localize changes in the regional cerebral blood flow (rCBF) with and without an auditory task of logatomes containing speech-like elements without meaningful context. The normal hearing ear was stimulated before implantation and after t

SUBMITTER: Peter N 

PROVIDER: S-EPMC10907329 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature