The Practice Change and Clinical Impact of Lung-Protective Ventilation Initiated in the Emergency Department: A Secondary Analysis of Individual Patient-Level Data From Prior Clinical Trials and Cohort Studies.

ABSTRACT:

Objectives

Mechanically ventilated emergency department (ED) patients experience high morbidity and mortality. In a prior trial at our center, ED-based lung-protective ventilation was associated with improved care delivery and outcomes. Whether this strategy has persisted in the years after the trial remains unclear. The objective was to assess practice change and clinical outcomes associated with ED lung-protective ventilation.

Design

Secondary analysis of individual patient-level data from prior clinical trials and cohort studies.

Setting

ED and ICUs of a single academic center.

Patients

Mechanically ventilated adults.

Interventions

A lung-protective ventilator protocol used as the default approach in the ED.

Measurements and main results

The pr

SUBMITTER: Fuller BM 

PROVIDER: S-EPMC10907984 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature