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Prognostic value of metabolic syndrome in patients with heart failure and malnutrition.


ABSTRACT:

Background

Malnutrition is severely associated with worst prognosis of patients with heart failure (HF). Malnourished patients with the metabolic syndrome (MS) can result in a double burden of malnutrition. We aimed to investigate the impact of the MS on clinical outcomes in malnourished HF patients.

Methods

We examined 529 HF patients at risk of malnutrition with a mean age of (66 ± 10) years and 78% (415) were male. Nutritional status defined primarily by the prognostic nutritional index (PNI), with PNI < 40 being defined as malnutrition. The follow-up endpoint was cardiovascular death or all-cause death.

Results

During the 36-month follow-up, survival rates for cardiovascular and all-cause death were significantly lower in the MS group than in the non-MS group (log

SUBMITTER: Zhang X 

PROVIDER: S-EPMC10908134 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature