Prognostic factors and outcomes of invasive pulmonary aspergillosis, a retrospective hospital-based study.

ABSTRACT:

Objective

Invasive pulmonary aspergillosis (IPA) affects immunocompromised hosts and is associated with higher risks of respiratory failure and mortality. However, the clinical outcomes of different IPA types have not been identified.

Methods

Between September 2002 and May 2021, we retrospectively enrolled patients with IPA in Taichung Veterans General Hospital, Taiwan. Cases were classified as possible IPA, probable IPA, proven IPA, and putative IPA according to EORTC/MSGERC criteria and the AspICU algorithm. Risk factors of respiratory failure, kidney failure, and mortality were analyzed by logistic regression. A total of 3-year survival was assessed by the Kaplan-Meier method with log-rank test for post-hoc comparisons.

Results

We included 125 IPA patients (

SUBMITTER: Chen WC 

PROVIDER: S-EPMC10908254 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature